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A lengthy-performing buprenorphine subdermal implant (Probuphine) was accepted because of the FDA in May possibly 2016 for use in opioid tolerant individuals who may have realized and sustained prolonged clinical steadiness on low-to-average doses of the transmucosal buprenorphine-containing item (ie, doses ≤eight mg/day of Subutex or Suboxone su

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